These cacti are native to the eastern and southern parts of Mexico and are characterised by columnar stems which eventually branch as they grow and reach nearly 15 metres in height. Like most columnar cacti, Neobuxbaumia juvenile plants vary considerably in appearance with respect to adult plants. Younger plants typically have more spines, while adult plants lose them, as the spines are dwarfed by the stem size. Despite the dense populations within their habitat, few species of Neobuxbaumia are found in cultivation, and it is unusual to find a private collector with one of these plants, also because of their size. Some botanical gardens, on the other hand, may have some specimens of this genus. Neobuxbaumia is quite easy to grow, but requires a well-draining mineral soil, lots of sun and ventilation.

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